Artificial Intelligence-Assisted Radiographic Diagnosis of Developmental Dysplasia of the Hip in Children: A Retrospective Study

Keywords: Developmental dysplasia of the hip, artificial intelligence, AutoML, pelvic radiography, children, deep learning

Abstract

Introduction: Developmental dysplasia of the hip (DDH) is the most common pediatric musculoskeletal disorder, and its radiographic diagnosis may be affected by technical and interpretive variability. Artificial intelligence (AI), particularly through automated machine learning (AutoML) platforms, offers tools to standardize image assessment and assist in diagnostic classification. Objectives: To develop and evaluate an AI model for distinguishing between normal pediatric pelvic radiographs and those showing DDH using the Landing Lens platform. Materials and Methods: A retrospective study included 328 pelvic radiographs from patients aged 1 month to 14 years. Four pediatric orthopedic surgeons with varying levels of experience independently labeled the images. The final diagnosis was established by a simple majority, with consensus reached in cases of disagreement. The radiographs were divided into training (70%), validation (20%), and test (10%) sets. Model performance was assessed using accuracy, recall, specificity, F1 score, and agreement coefficients. Results: The model correctly classified 320 images (accuracy, 97.6%; recall, 92.8%; specificity, 98%; F1 score, 86.6%). Interobserver agreement was almost perfect (Fleiss’ kappa, 0.86), and agreement between the model and specialists increased with clinical experience (Cohen’s kappa, 0.85 for the senior observer). Conclusions: These findings support the use of AI as an adjunctive tool to standardize the radiographic diagnosis of DDH and reduce interobserver variability. External validation and multicenter studies are required before routine clinical implementation.

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Author Biographies

Melina I. Luna, Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina
Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina
Román Bertolotti, Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina
Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina
Gerardo M. Ferrer, Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina
Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina
Antonio E. Pedro Maraude, Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina
Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina
Miguel C. González, Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina
Orthopedics and Traumatology Service, Hospital de Niños de la Santísima Trinidad de Córdoba, Córdoba, Argentina

References

Chen M, Cai R, Zhang A, Chi X, Qian J. The diagnostic value of artificial intelligence-assisted imaging for

developmental dysplasia of the hip: a systematic review and meta-analysis. J Orthop Surg Res 2024;19(1):522.

https://doi.org/10.1186/s13018-024-05003-4

Jan F, Rahman A, Busaleh R, Alwarthan H, Aljaser S, Al-Towailib S, et al. Assessing acetabular index angle in

infants: A deep learning-based novel approach. J Imaging 2023;9(11):242. https://doi.org/10.3390/jimaging9110242

Xu W, Shu L, Gong P, Huang C, Xu J, Zhao J, et al. A deep-learning aided diagnostic system in assessing

developmental dysplasia of the hip on pediatric pelvic radiographs. Front Pediatr 2021;9:785480.

https://doi.org/10.3389/fped.2021.785480

Fraiwan M, Al-Kofahi N, Ibnian A, Hanatleh O. Detection of developmental dysplasia of the hip in X-ray images

using deep transfer learning. BMC Med Inform Decis Mak 2022;22(1):216. https://doi.org/10.1186/s12911-022-01957-9

Chen J, Fan X, Chen Z, Peng Y, Liang L, Su C, et al. Enhancing YOLO5 for the assessment of irregular pelvic

radiographs with multimodal information. J Imaging Inform Med 2024;37(2):744-55.

https://doi.org/10.1007/s10278-024-00986-2

Zhang SC, Sun J, Liu CB, Fang JH, Xie HT, Ning B. Clinical application of artificial intelligence-assisted diagnosis

using anteroposterior pelvic radiographs in children with developmental dysplasia of the hip. Bone Joint J 2020;102-B(11):1574-81. https://doi.org/10.1302/0301-620X.102B11.BJJ-2020-0712.R2

Park HS, Jeon K, Cho YJ, Kim SW, Lee SB, Choi G, et al. Diagnostic performance of a new convolutional neural

network algorithm for detecting developmental dysplasia of the hip on anteroposterior radiographs. Korean J Radiol 2021;22(4):612-23. https://doi.org/10.3348/kjr.2020.0051

Liu C, Xie H, Zhang S, Mao Z, Sun J, Zhang Y. Misshapen pelvis landmark detection with local-global feature

learning for diagnosing developmental dysplasia of the hip. IEEE Trans Med Imaging 2020;39(12):3944-54.

https://doi.org/10.1109/TMI.2020.3008382

Qi G, Jiao X, Li J, Qin C, Li X, Sun Z, et al. A dataset for quality evaluation of pelvic X-ray and diagnosis of

developmental dysplasia of the hip. Sci Data 2025;12(1):865. https://doi.org/10.1038/s41597-025-05146-x

Sha J, Huang L, Chen Y, Fan Z, Lin J, Yang Q, et al. Clinical thought-based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographs. Front Pediatr 2023;11:1080194.

https://doi.org/10.3389/fped.2023.1080194

Perry S, Folkman M, O’Brien T, Wilson L, Coyle E, Liu R, et al. Unaligned hip radiograph assessment utilizing

convolutional neural networks for the assessment of developmental dysplasia of the hip. J Eng Sci Med Diagn Ther 2024;7(4):041003. https://doi.org/10.1115/1.4064988

Segura F, Segura P, Segura F. Determinación del grado de agresividad tumoral mediante técnicas de inteligencia artificial aplicadas a imágenes de resonancia magnética. Rev Asoc Argent Ortop Traumatol 2023;88(6):653-61. https://doi.org/10.15417/issn.1852-7434.2023.88.6.1738

Bayliss L, Jones LD. The role of artificial intelligence and machine learning in predicting orthopaedic outcomes. Bone Joint J 2019;101-B(12):1476-8. https://doi.org/10.1302/0301-620X.101B12.BJJ-2019-0850.R1

Segura FM, Segura FP, Zudaire MPL, Segura FV. Advances in Artificial Intelligence for automated knee

osteoarthritis classification using the IKDC system. Eur J Orthop Surg Traumatol 2024;35(1):32.

https://doi.org/10.1007/s00590-024-04124-0

Den H, Ito J, Kokaze A. Diagnostic accuracy of a deep learning model using YOLOv5 for detecting developmental dysplasia of the hip on radiography images. Sci Rep 2023;13(1):6693. https://doi.org/10.1038/s41598-023-33860-2

Lv J, Che J, Chen X. CBA-YOLOv5s: A hip dysplasia detection algorithm based on YOLOv5s using angle consistency and bi-level routing attention. Biomed Signal Process Control 2024;95:106482.

https://doi.org/10.1016/j.bspc.2024.106482

Sha J, Huang L, Chen Y, Lin J, Fan Z, Li Y, et al. A novel approach for screening standard anteroposterior pelvic

radiographs in children. Eur J Pediatr 2023;182(11):4983-91. https://doi.org/10.1007/s00431-023-05164-0

Gartland CN, Healy J, Lynham RS, Nowlan NC, Green C, Redmond SJ. Automated system of analysis to quantify

pediatric hip morphology. Comput Biol Med 2025;197:110904. https://doi.org/10.1016/j.compbiomed.2025.110904

van Kouswijk HW, Yazid H, Schoones JW, Witlox MA, Nelissen RGH, de Witte PB. Current and emerging

applications of artificial intelligence in medical imaging for paediatric hip disorders: a scoping review. Children

;12(5):645. https://doi.org/10.3390/children12050645

Bhavsar S, Gowda BB, Bhavsar M, Patole S, Rao S, Rath C. Artificial intelligence to detect developmental dysplasia of hip: A systematic review. J Paediatr Child Health 2025;61(11):1712-27. https://doi.org/10.1111/jpc.70172

McArthur A, Wichuk S, Burnside S, Kirby A, Scammon A, Sol D, et al. Retuve: Automated multi-modality analysis of hip dysplasia with open source AI. arXiv 2025;:2504.06422. https://doi.org/10.48550/ARXIV.2504.06422

Published
2026-10-27
How to Cite
Luna, M. I., Bertolotti, R., Ferrer, G. M., Pedro Maraude, A. E., & González, M. C. (2026). Artificial Intelligence-Assisted Radiographic Diagnosis of Developmental Dysplasia of the Hip in Children: A Retrospective Study. Revista De La Asociación Argentina De Ortopedia Y Traumatología, 91(5), 420-426. https://doi.org/10.15417/issn.1852-7434.2026.91.5.2281
Section
Clinical Research